Coverage & method

How the dataset is built.

Decision-grade intelligence needs traceable sources. This page explains how the LAI dataset is scoped, classified and sourced.

The boundary

What counts as a long-acting injectable.

The scope is a deliberate, documented decision, revisited as the field evolves. An asset is in scope when its long duration is engineered: obtained from an identifiable delivery or half-life-extension technology, by an injectable route, and lasting far longer than the drug would on its own. Deliberately out of scope: vaccines, cell and gene therapies, surgically-placed or non-resorbable implants, and antibodies whose long half-life is natural rather than engineered.

The technology map

The technology, classified.

In an LAI, duration of action comes from the technology: a drug delivery system that controls release, or a half-life extension that modifies the molecule. Assets are classified on independent axes that combine: an asset can be a physical depot, of a given matrix, on a given route.

Drug delivery systems (DDS)
Physical release
MicrosphereNanocrystalEngineered particleIn-situ depotGel depotImplantLiposomeOil depot
Chemical release
Prodrug (ester, amide)Cleavable conjugate
Matrix material
PolymerLipidHydrogelInorganic
Half-life extension (HLE)
Mechanism
PEGylationLipidationAlbumin-bindingFc-fusionGlyco-engineeringProtein-fusion extender
Inputs & cadence

Public inputs, monitored year-round.

The raw material is public: regulatory bodies such as the FDA and EMA, clinical registries, the scientific literature, corporate disclosures. Sources are monitored continuously and the dataset is updated as the field moves. The ontology, the delivery-technology taxonomy and the curation decisions that consolidate each entity into a single record are proprietary.

Provenance

Where each value comes from.

Regulatory facts, linked to source

Where an FDA or EMA label exists, its facts carry a link to the official source: DailyMed for the FDA, the EMA register.

Everything else, curated to the ontology

Delivery technology, release families, molecular properties, targets and other attributes are sourced from company disclosures, ClinicalTrials.gov, PubMed and ChEMBL, then curated and standardized in Vectora’s ontology for consistent comparison across the scope.

Curation

Governed by domain expertise.

The ontology, the delivery-technology taxonomy, and the scope are defined and maintained by a specialist in pharmaceutical competitive intelligence. These editorial decisions (which assets qualify, how each technology is classified) are specific to the LAI field.

Access for LAI teams.

Vectora is available to teams working in Long-Acting Injectables.

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